Abstract
Human papillomavirus type 16 (HPV16), a member of the Papillomaviridae family, is the primary etiological agent of cervical cancer. Here, we report the complete genome sequences of four HPV16 Asian American variants and four European variants, isolated from cervical biopsies and scrapings in India.
Highlights
Human papillomavirus type 16 (HPV16), a member of the Papillomaviridae family, is the primary etiological agent of cervical cancer
Corresponding to geographical regions, HPV16 is classified into five variant lineages [3,4,5], namely, European (E), Asian (A), Asian American (AA), African-1 (Af1), and African-2 (Af2)
In India, HPV16 has been found to be the most prevalent highrisk type associated with CaCx cases [6], and, in an earlier report from our laboratory, the presence of AA variants was confirmed for the first time along with E variants using Sanger sequencing [7,8,9]
Summary
Human papillomavirus type 16 (HPV16), a member of the Papillomaviridae family, is the primary etiological agent of cervical cancer. In India, HPV16 has been found to be the most prevalent highrisk type associated with CaCx cases [6], and, in an earlier report from our laboratory, the presence of AA variants was confirmed for the first time along with E variants using Sanger sequencing [7,8,9].
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