Abstract
The bacteriophage LSPA1 was isolated from hospital sewage (Kunming, China), and lytic activity was demonstrated against the Salmonella enterica serovar Paratyphi A CMCC50973 strain. This bacteriophage has a 41,880-bp double-stranded DNA (dsDNA) genome encoding 58 coding sequences (CDSs) and belongs to the family Siphoviridae.
Highlights
The bacteriophage LSPA1 was isolated from hospital sewage (Kunming, China), and lytic activity was demonstrated against the Salmonella enterica serovar Paratyphi A CMCC50973 strain
Understanding Salmonella enterica serovar Paratyphi A phages is important for extending our knowledge and use of phage therapy
The strictly lytic phage LSPA1 was isolated from hospital sewage in Kunming, Southwest China, using the violent strain CMCC50973 of Salmonella Paratyphi A as the host
Summary
The bacteriophage LSPA1 was isolated from hospital sewage (Kunming, China), and lytic activity was demonstrated against the Salmonella enterica serovar Paratyphi A CMCC50973 strain. Paratyphoid fever outbreaks sharply increased in recent years in Asia [1, 2], and its antibiotic resistance is increasing [3, 4]. Understanding Salmonella enterica serovar Paratyphi A phages is important for extending our knowledge and use of phage therapy. The strictly lytic phage LSPA1 was isolated from hospital sewage in Kunming, Southwest China, using the violent strain CMCC50973 of Salmonella Paratyphi A as the host.
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