Abstract
Macrolide-resistant Mycoplasma pneumoniae strains can cause severe M. pneumoniae pneumonia in children. Here, we report the complete genome sequence of the macrolide-resistant M. pneumoniae strain C267, deposited in GenBank under accession number CP014267, which provides new insights for other potential macrolide-resistant mechanisms in M. pneumoniae clinical isolates in China.
Highlights
Macrolide-resistant Mycoplasma pneumoniae strains can cause severe M. pneumoniae pneumonia in children
Macrolide-resistant Mycoplasma pneumoniae (MRMP) strains, which are defined by point mutations in 23S rRNA genes, have increased rapidly worldwide since 2000 [1, 2], especially in South Korea, China, and Japan [3,4,5]
Why have M. pneumoniae resistance rates been so high in Asia? To answer this question, there is a need for whole-genome sequencing of MRMP isolated from Asia to fully comprehend its mechanism
Summary
Macrolide-resistant Mycoplasma pneumoniae strains can cause severe M. pneumoniae pneumonia in children. Macrolide-resistant Mycoplasma pneumoniae (MRMP) strains, which are defined by point mutations in 23S rRNA genes, have increased rapidly worldwide since 2000 [1, 2], especially in South Korea, China, and Japan [3,4,5]. MRMP can cause severe M. pneumoniae pneumonia in children [1]. Why have M. pneumoniae resistance rates been so high in Asia?
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