Abstract
Respiratory disease caused by Mannheimia haemolytica is a major concern in the cattle and small stock industry worldwide. This problem arises due to the interaction of numerous contributing factors, including physical stresses associated with weaning, shipment, inclement weather, and overcrowding coupled with viral and bacterial infections. The whole genome of M. haemolytica strain Mh10517 was analyzed using an Illumina MiSeq high-throughput sequencing platform. The genome size is 2.67 Mb with 2,879 predicted gene sequences. The availability of this genome sequence will advance studies on various aspects of the biology of M. haemolytica in Africa and the world at large.
Highlights
Respiratory disease caused by Mannheimia haemolytica is a major concern in the cattle and small stock industry worldwide
We report the draft genome sequence of M. haemolytica strain Mh10517 isolated from the lung tissue of sheep with a history of respiratory infections in South Africa in 1966
This will be the first genome sequence of M. haemolytica isolated from Africa
Summary
Respiratory disease caused by Mannheimia haemolytica is a major concern in the cattle and small stock industry worldwide. Mannheimia haemolytica is a facultative pathogen, a Gramnegative coccobacillus, and a commensal of the upper respiratory tract and nasopharynx of ruminant hosts [1, 2], but in the presence of stress factors, such as weaning, transportation, poor nutrition, and various viral infections, the bacterium multiplies and often results in fatal fibrinous pleuropneumonia, known as pneumonic pasteurellosis or shipping fever [3,4,5,6,7,8,9,10]. Genome sequences of M. haemolytica isolated from cattle [11] and sheep [10] in the United States have been determined and various putative genes with assigned functions were revealed. We report the draft genome sequence of M. haemolytica strain Mh10517 isolated from the lung tissue of sheep with a history of respiratory infections in South Africa in 1966.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
