Abstract
Lactobacilli can exert health-promoting effects in the human oral microbiome through many mechanisms, including pathogen inhibition, maintenance of microbial balance, immunomodulation, and enhancement of the epithelial barrier function. Here, we present the complete genome sequence of a potential probiotic, Lactobacillus oris J-1, that was isolated from the oral cavity of a health child.
Highlights
Lactobacilli can exert health-promoting effects in the human oral microbiome through many mechanisms, including pathogen inhibition, maintenance of microbial balance, immunomodulation, and enhancement of the epithelial barrier function
Lactobacillus oris J-1, which was isolated from the oral cavity of a healthy child, was found to be beneficial as a potential probiotic
We present the complete sequence of this strain, which is the first complete genome sequence of L. oris
Summary
Lactobacilli can exert health-promoting effects in the human oral microbiome through many mechanisms, including pathogen inhibition, maintenance of microbial balance, immunomodulation, and enhancement of the epithelial barrier function. Lactobacilli, the acidophilic and aciduric Gram-positive bacteria of the genus Lactobacillus, belong to the indigenous microflora of humans and colonize various parts of the human body (1). Lactobacillus oris J-1, which was isolated from the oral cavity of a healthy child, was found to be beneficial as a potential probiotic. We present the complete sequence of this strain, which is the first complete genome sequence of L. oris.
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