Abstract
Bacteriophage Miami infects Klebsiella pneumoniae, a Gram-negative pathogen that is becoming an increasing threat to public health due to its multidrug resistance. Here, we describe the annotation of the 253,383-bp jumbo phage Miami genome sequence and its similarity to other myophages.
Highlights
Klebsiella pneumoniae is a Gram-negative, encapsulated, nonmotile bacterium that can be found in soil, water, and on human mucosal surfaces [1]
The genome G1C content is 43.9%, which is lower than the average G1C content of K. pneumoniae
Miami shares 105 proteins similar to those in Vibrio phages 2 TSL-2019, USC-1, Aphrodite1, and 5 TSL-2019, which are classified in the genus Aphroditevirus (MK368614, MK905543, MG720308, and MK358448, respectively). progressiveMauve analyses determined that Miami shares the highest nucleotide identity with Erwinia phage Rising Sun at 11.4%
Summary
Klebsiella pneumoniae is a Gram-negative, encapsulated, nonmotile bacterium that can be found in soil, water, and on human mucosal surfaces [1]. Miami possesses a 253,383-bp genome with a coding density of 94% and 300 predicted protein-coding genes, only 47 of which have a predicted function. The genome G1C content is 43.9%, which is lower than the average G1C content of K. pneumoniae
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