Complete Genome Sequence of an Avian Polyomavirus Strain First Isolated from a Pigeon in China.

Qiuchen Li,Yu Feng,Haojie Sun,Shijing Sun,Fang Wang,Hui Jiang,Jiabo Ding,Kai Niu,Yingju Xia,Liangquan Zhu,Guanlong Xu,Xuezheng Fan,Jie Li,Yuming Qin,Xiaowei Peng,Julie C Dunning Hotopp

doi:10.1128/mra.01490-18

Abstract

Avian polyomavirus can infect multiple bird species and cause inflammatory disease with high mortality in young psittacine birds. In this study, we sequenced and analyzed an avian polyomavirus isolated from a pigeon in China, strain APV-P, which is closely related to a polyomavirus in psittacine birds.

Highlights

Avian polyomavirus can infect multiple bird species and cause inflammatory disease with high mortality in young psittacine birds
Frame (ORF) is located within the VP2 ORF, and the amino acid sequence of VP3 is identical to the sequence of the C terminus (235 aa) of VP2
The VP4Delta protein shares the same amino acid sequence with VP4 except it is truncated between amino acids 68 and 131

Summary

Introduction

Avian polyomavirus can infect multiple bird species and cause inflammatory disease with high mortality in young psittacine birds. The genome of the APV-P isolate was found to be circular and 4,981 bp in length, with 49% GC content. The genome structure of the APV-P isolate is similar to those of avian polyomaviruses and contains a noncoding control region (NCCR) and early and late regions.

Results

Conclusion