Abstract
A canine rabies virus (RABV) was isolated from a trade dog in Nigeria. Its entire genome was sequenced and found to be closely related to canine RABVs circulating in Africa. Sequence comparison indicates that the virus is closely related to the Africa 2 RABV lineage. The virus is now termed DRV-NG11.
Highlights
A canine rabies virus (RABV) was isolated from a trade dog in Nigeria
On the basis of phylogenetic analysis of the nucleoprotein (N) and/or the glycoprotein (G) gene sequences, all RABVs have been divided into two major clades, one comprising those isolated from terrestrial animals around the world and the other containing viruses isolated from bats and raccoons in the Americas [4,5,6,7]
A strain of RABV was isolated from a dog brain originating in Nigeria and was designated DRV-NG11
Summary
A canine rabies virus (RABV) was isolated from a trade dog in Nigeria. Its entire genome was sequenced and found to be closely related to canine RABVs circulating in Africa. Rabies, which can cause an almost invariably fatal encephalomyelitis, remains a public health threat around the world. Effective vaccines are available, more than 55,000 people still die from rabies each year throughout the world, with most of them in developing countries of Asia and Africa [1].
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