Abstract
ABSTRACTThe NADC30-like strains of porcine reproductive and respiratory syndrome virus (PRRSV) are characterized by a 131-amino-acid deletion in nonstructural protein 2 (NSP2). Here, we report the complete genome sequence of a recombinant NADC30-like PRRSV strain, SCnj16, that exhibits the molecular marker of the Chinese highly pathogenic PRRSV (HP-PRRSV) in NSP2.
Highlights
The NADC30-like strains of porcine reproductive and respiratory syndrome virus (PRRSV) are characterized by a 131-amino-acid deletion in nonstructural protein 2 (NSP2)
Based on the results of the similarity plot and phylogenetic analysis, we speculate that SCnj[16] likely originated from recombination events between the NADC30-like and Chinese HP-PRRSV strains at three recombination breakpoints; the first was located in nsp[2], the second in nsp[3], and the third in nsp[9]
All authors have read and approved the submitted manuscript
Summary
The NADC30-like strains of porcine reproductive and respiratory syndrome virus (PRRSV) are characterized by a 131-amino-acid deletion in nonstructural protein 2 (NSP2). The complete genomic sequence of SCnj[16] is 15,321 nucleotides (nt) in length, excluding the poly(A) tail.
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