Abstract
The full-length genome sequence of a novel swine acute diarrhea syndrome coronavirus (SADS-CoV), CH/FJWT/2018, was determined, which was genetically most closely related to CN/GDWT/2017, recently discovered in Fujian, China. The indel sites of the spike (S) gene of CH/FJWT/2018 were most similar to those of bat-origin SADS-related coronaviruses.
Highlights
Swine acute diarrhea syndrome coronavirus (SADS-CoV) belongs to the genus Alphacoronavirus in the family Coronaviridae and is an enveloped, positive-sense, single-stranded RNA virus [1]
The results of a phylogenetic analysis using Molecular Evolutionary Genetics Analysis (MEGA) v7.0 [9], based on CH/FJWT/2018 and other reference sequences of SADS-CoVs retrieved from GenBank, showed that CH/FJWT/2018 had 99.6% nt identity with CN/GDWT/2017 (GenBank accession number MG557844), a swine-origin SADS
The insertion/deletion patterns of CH/FJWT/2018 were more similar to those of bat-origin SADS-related coronaviruses (SADSr-CoVs) [6] than to those of swine-origin SADS-CoVs, suggesting that CH/FJWT/2018 might originate from bats
Summary
Swine acute diarrhea syndrome coronavirus (SADS-CoV) belongs to the genus Alphacoronavirus in the family Coronaviridae and is an enveloped, positive-sense, single-stranded RNA virus [1]. The complete genome sequence of CH/FJWT/2018 determined was 27,169 nt in length, excluding the 3= poly(A) tail.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
