Abstract

Patients with idiopathic Parkinson’s disease (IPD) require long-term care and are reported to use complementary and alternative medicine (CAM) interventions frequently. This CAM-specific clinical practice guideline (CPG) makes recommendations for the use of CAM, including herbal medicines, acupuncture, moxibustion, pharmaco-acupuncture, and qigong (with Tai chi) in patients with IPD. This guideline was developed using an evidence-based approach with randomized controlled trials currently available. Even though this CPG had some limitations, mainly originating from the bias inherent in the research on which it is based, it would be helpful when assessing the value of the CAM interventions frequently used in patients with IPD.

Highlights

  • Idiopathic Parkinson’s disease is a chronic neurodegenerative disease which presents progressive loss of dopaminergic neurons in substantia nigra

  • This complementary and alternative medicine (CAM)-specific clinical practice guideline (CPG) for idiopathic Parkinson’s disease (IPD) was developed by the Society of Stroke on Korean medicine (KM) (Figure 1)

  • Inclusion of multiple prescriptions when assessing the clinical evidence for herbal medicine is controversial, it is considered necessary at the present stage

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Summary

Introduction

Idiopathic Parkinson’s disease is a chronic neurodegenerative disease which presents progressive loss of dopaminergic neurons in substantia nigra. Long-term medical care is often required after first diagnosis of IPD. The prevalence of IPD rises with age but there could be geographic difference in the prevalence among 70–79-year-old population between Asian countries and North America–Europe countries (Pringsheim et al, 2014). Because disease modifying therapy for IPD is absent and patients with IPD have unmet needs which are introduced from undesirable symptoms related to the conventional levodopa therapy and various non-motor symptoms (Bastide et al, 2015), many IPD patients use various complementary and alternative therapies currently.

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