Abstract
Bidens pilosa L. is a cosmopolitan annual herb, known for its traditional use in treating various diseases and thus much studied for the biological activity of its extracts, fractions and isolated compounds. Polyacetylenes and flavonoids, typical metabolite classes in the Bidens genus, predominate in the phytochemistry of B. pilosa. These classes of compounds have great taxonomic significance. In the Asteraceae family, the acetylene moiety is widely distributed in the Heliantheae tribe and some representatives, such as 1-phenylhepta-1,3,5-triyne, are noted for their biological activity and strong long-wave UV radiation absorbance. The flavonoids, specifically aurones and chalcones, have been reported as good sub-tribal level markers. Natural products from several other classes have also been isolated from different parts of B. pilosa. This review summarizes the available information on the 198 natural products isolated to date from B. pilosa.
Highlights
The genus Bidens (Asteraceae: Heliantheae) comprises about 240 species with cosmopolitan distribution [1]
Interesting relationships within the Heliantheae, as well as its relationship with other tribes have been proposed on the basis of various types of compounds found in the tribe, especially acetylenes, sesquiterpene lactones and flavonoids [4,5]
Bidens pilosa L. (Figure 1) stands out among the species of the genus due to the large number of natural products characterized in it and the biological activities reported for its extracts, fractions and compounds
Summary
Compilation of Secondary Metabolites from Bidens pilosa L. Fabiana Lima Silva 1,2,*, Dominique Corinne Hermine Fischer 2, Josean Fechine Tavares 1, Marcelo Sobral Silva 1, Petronio Filgueiras de Athayde-Filho 1 and Jose Maria Barbosa-Filho 1,*. Departamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Av. Received: 11 November 2010; in revised form: 13 January 2011 / Accepted: 24 January 2011 /
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