Abstract
Intraoperative acute isovolemic hemodilution has been used to decrease the need for homologous blood transfusion. Decreased arterial oxygen content and total oxygen delivery to tissues promote a compensatory increase in cardiac output, related to the hemodilution-induced decrease in viscosity and/or vasodilatation, preserving tissue oxygen delivery. Regional blood flow distribution may vary widely between and within organs. Splanchnic hypoperfusion, particularly at the intestinal mucosal region, has been implicated in systemic inflammatory response and multiple organ dysfunction. We evaluated systemic and splanchnic oxygen-derived variables during a moderate acute isovolemic hemodilution to test the hypothesis that hemodilution may promote gastric mucosal acidosis, despite an apparent adequacy of global markers of oxygen delivery and consumption.
Highlights
Propranolol plasma levels and pharmacokinetics (PK) may be altered by cardiopulmonary bypass (CPB)
Analysis of data from a retrospective study of long distance aeromedical transports performed by Montreal-based Skyservice Lifeguard transport service. (A manuscript describing this study has been accepted for publication in the journal Aviation, Space, and Environmental Medicine.) For patients transported by Lear Jet air ambulance post myocardial infarction (MI), potential risk factors examined included age, gender, Killip class, revascularization procedures, and status at time of transportation
TST was positive for myocardial ischemia in 22% of 82 patients initially classified as intermediate probability of acute myocardial infarction (AMI)/unstable angina (UA), and in 9% of 186 patients classified as low probability (P = 0.004)
Summary
Propranolol plasma levels and pharmacokinetics (PK) may be altered by cardiopulmonary bypass (CPB). The objective of our study was to assess the effect of different levels of airway pressure on lung morphology by performing a LRM during the lung CT-scan This way, we could set the best ventilatory strategy for the patient and identify the mechanisms involved during the LRM. The goal of this study was to determine the incidence of thrombocytopenia and the correlation with length of ICU stay, mortality rate, admission severity scores APACHE II and SAPS II, and multiple organ dysfunction scores SOFA and LODS. Multiple organ dysfunction has been recognized as a major factor associated with mortality in patients with acute respiratory failure (ARF). Purpose: The objectives of this study are (1) to describe demographics, clinical features, physiologic parameters, and prognosis of patients on mechanical ventilation admitted to the Intensive Care Unit of Hospital Moinhos de Vento; and (2) to identify predictors of mortality and ventilator time. Percutaneous access is an option in such patients, and the clinical staff can perform it
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