Comparsion Between Anti Coccidial Effectes of Artemisia Siberi Extract and Apacox Copmplex and Lasalosid in Experimental Infected Broilers with Coccidiosis

Abstract

Increasing resistance against conventional anticoccidial drugs and consequence of their residues has paid the attention toward more effective and safe compounds. Artemisia plant and the apacox complex are potential candidates that their anticoccidial effects has been previously discusse: This study aimed to determin an appropriate dosage from the extract of Artemisia siberi and evaluate its anticcocidial effects compared to apacox complex and lasalosid drug. Artemisinin extract was extracted from Artemisia siberi by petroleum ether the apacox complex and lasalosid bought from the pharmacy by our order.105 chicks were divided in to 7 group tree replicates each (n=15).artemisia extract in two dosages 0/5 and 1/5 mg/kg for group A &B and the apacox complex in two dosages 0/5 and 1/5 gr/kg for group C&D and lasalosid in 75 mg/kg were used for the E group of broilers from the first day as feed additive . infected group(F) and non infected group(G) didn’t recive any medication . Experimental coccidiosis was induced in chicks by oral administration of 100000 oocysts/chick on 14 th day . fecal samples of each group were collected for 5 days from 15th day until 19th day and the OPG (oocyst per gram) was determined as anticoccidial index. Artemisia and apacox complex significantly decreased OPG value in treated group although it was lower than lasalosid group .artemisia extract in 1/5 mg /kg had stronger power than apacox in its two dosage and Artemisia in 0/5 mg/kg .this means Artemisia have dependent dosage effect in dosage lower than 1/5 mg/kg. This study showed that the Artemisia siberi extract can be considered as a new effective and safe anticoccidial drug although it is weaker than lasalosid