Abstract
Background: Escherichia coliis a normal intestinal flora that have contributions on the normal functioning of human digestion, but it will turn into a pathogen when it is outside the intestinal tract. E. coli including family Enterobacteriaceae, facultative anaerobic. Characteristics of E. coli is a bacteria gram-negative rod-shaped, motile with flagella or nonmotile, fermentation of glucose, and producing gas. Chitosan has antimicrobial effect against bacteria. Amine moieties of chitosancontent positively charged which is very reactive, and have the ability to bind with the cell walls of bacteria are negative charged. Amine cluster also has a free electron pair, so it was able to attract minerals Ca2+ in the cell walls of bacteria.Objective: to know the comparative effectiveness of chitosanon the shell of a small crab attaching with ciprofloxacin antibiotics against the development of the bacteria E. coli.Methods: this research uses experimental methods. Techniques used in measuring antimicrobial activity is the diffusion disc method.Results: the results showed that the average diameter of the inhibitory zones of chitosanagainst E. coli in a row with a concentration of 4%, 5%, 6%, 7%, and 8% is 14.22 mm, 11.94 mm, 9.18 mm, 11.19 mm, and 8.76 mm. Whereas the average diameter of the inhibitory zones of ciprofloxacin is 42.31 mm.Conclusion: Chitosanon small crab attaching shells with a concentration of the most effective in inhibiting the development of the bacteria E. coli is chitosanwith concentrations of 4% with the average drag zone amounting to 14,22 mm.International Journal of Human and Health Sciences Vol. 02 No. 04 October’18. Page : 217-219
Highlights
IntroductionInfection is an illness to who caused by microbes pathogenic.One of the cause is that bacteria
Infection is a cause of increased rates of morbidity and mortalities especially on developing countries such as Indonesia
Data Analysis The data obtained of the study are the primary data was the results of research that is a comparison of the effectiveness of chitosan with antibiotics ciprofloxacin to the development of bacteria E. coli by measuring wide clear zone around paper compact discs containingchitosan and ciprofloxacin
Summary
Infection is an illness to who caused by microbes pathogenic.One of the cause is that bacteria. Thefluoroquinolone are still recommended as an antibiotic prophylactic infections of the urinary tract because fluoroquinolone having the power of a strong antibacterial especially against E. coli. In the near future it has been much it has been reported about of resistance from the the companions of the fluoroquinolone especially ciprofloxacin as prophylactic therapy infections of the urinary tract of the tariffs range from 20 % -30. %5.Indonesia produced any type of waste you the shell of a crab, the skin or the head of shrimp, and other marine animals not less than 56.200 metric tons. Chitosan having the nature of disturbing activity outer membrane gram-negative bacteria
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
