Comparison study on operative trauma between endoscopic thyroidectomy and traditional thyroidectomy

Abstract

Objective To explore the injury of endoscopic thyroidectomy via breast areola approach and the anterior chest wall to human body. Methods Sixty patients with thyroid benign tumor, hospitalized from Janurary 2009 to December 2010, were divided into endoscopic thyroidectomy group and traditional thyroid surgery group with respect of the patients' own willing. The levels of interleukin (IL)-2,IL-6, C-reactive protein ( CRP), tumor necrosis factor (TNF)-o in the blood were determined 2 h, 1 day and 3 days after surgery. Results No statistically significant difference was found between the 2 groups in the levels of IL-2[endoscopic group: ( 12. 6 ± 2. 1 ), ( 11.8 ± 1.9), ( 11.8 ± 3.0) ng/L; traditional group: (10.6±1.1), (11.2±2.6), (12.0 ±3.2) ng/L], CRP[endoscopic group: (1.6±0.7),(2.4±0.9), (2.5±0.9) mg,/L; traditional group: (0.8±0.6), (2.4±0.5), (2.4±0.7) mg/L],TNF-αt[endoscopic group: (53.2 ±6. 8), (49. 1 ±5.5), (46. 5 ±5.0) ng/L; traditional group: (48. 5±7. 1 ), (51.3 ±6. 2), (41.5 ± 13.7) ng/L]at different time points. The levels of IL-6 showed significant difference between two groups at 2nd h and first day after surgery ( P ＜ 0. 05 )[endoscopic group:(4.8 ±2.4), (4.3 ±2. 1), (5.4 ±5.6) ng/L; traditional group: (6.4±2.4), (7. 1 ±4. 1), (4.9 ±0. 8) ng/L]. Conclusion Compared with traditional surgery, endoscopic thyroidectomy is relatively minimally invasive and worthy of being widely applied for its preservation of the outlook of patients and not increasing the injury to patients. Key words: Thyroid benign tumor; Endoscopic thyroidectomy