Comparison on effect of laparoscopic cholecystectomy and open cholecystectomy for elderly patients with acute cholecystitis

Abstract

Objective To compare the specific effects of laparoscopic cholecystectomy (LC) and open cholecystectomy (OC) in the treatment of elderly patients with acute cholecystitis. Methods A total of 86 elderly patients with acute cholecystitis in Yongji Traditional Chinese Medicine Hospital from January 2015 to December 2017 were selected. They were randomly divided into control group and research group, with 43 cases in each group. The study group underwent laparoscopic cholecystectomy, while the control group underwent open cholecystectomy. Effects of laparoscopic cholecystectomy and open cholecystectomy in the treatment of elderly acute cholecystitis were compared. Results The operation time in the control group was less than that in the study group(P 0.05). Levels of CD3+ , CD4+ /CD8+ , IgA, IgG and IgM in the study group after operation were compared with those before operation, and there was no significant difference(P>0.05). The levels of CD3+ , CD4+ /CD8+ , IgA, IgG and IgM in the control group were significantly lower than those before operation (P all< 0.05). Conclusions Laparoscopic cholecystectomy is effective and safe in the treatment of acute cholecystitis in elderly patients, which is conductive to ensuring the prognosis and quality of life of patients. Key words: Laparoscopic cholecystectomy; Open cholecystectomy; Elderly, acute cholecystitis