Abstract
AbstractThe present study employed 2,2‐diphenyl‐l‐picrylhydrazyl (DPPH) radical‐scavenging and xanthine–xanthine oxidase (XO) assays to compare the antioxidant capacity between two plant adaptogens, Eleutherococcus senticosus (Araliaceae) and Rhodiola rosea (Crassulaceae). The IC50 value for XO activity for Rhodiola was 355.4 µg/ml, while that for Eleutherococcus was >1,000 µg/ml. Eleutherococcus inhibited DPPH generation by 58.3±2.8% at 1,000 µg/ml, whereas Rhodiola inhibited DPPH radical by 91.1±2.6% at the same concentration. The results suggested that Rhodiola inhibited not only XO but also served as a potent radical scavenger. Rhodiola has potential as a natural source of antioxidants. Drug Dev Res 71:249–252, 2010. © 2010 Wiley‐Liss, Inc.
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