Abstract
Objective: To investigate the dosimetric advantages of volumetric modulated arc therapy over intensity-modulated radiation therapy for radical treatment of early-stage prostate cancer.
 Study Design: Retrospective longitudinal study.
 Place and Duration of Study: Department of Radiation Oncology, Combined Military Hospital, Rawalpindi Pakistan, from Jan to Jun 2019.
 Methodology: Two treatment plans; one volumetric modulated arc therapy and other intensity-modulated radiation therapy, were made for 13 patients undergoing radical radiotherapy for early prostate cancer. Conformity index, Homogeneity index, the volume of rectum and bladder receiving a dose of 50 Gy or more, monitor units employed and treatment delivery time were compared between both techniques.
 Results: Volumetric modulated arc therapy plans showed statistically better conformity index and Homogeneity index with significantly lower doses to the rectum and bladder than intensity-modulated radiation therapy plans. The number of monitor units (MUs) employed and treatment delivery time were also reduced significantly with volumetric modulated arc therapy.
 Conclusion: Volumetric modulated arc therapy generates dose-metrically better radiotherapy plans than intensity-modulated radiation therapy and can deliver the required dose faster.Keywords: Hypofractionated radiotherapy, Intensity-modulated radiation therapy, Prostate cancer, Volumetric modulated arc therapy.
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