Abstract

No statistical differences in virulence were found among five clones isolated from each of two Trichomonas vaginalis strains JH31A and Balt 42. The former strain, isolated from a patient showing no cervical epithelial abnormalities, caused relatively small subcutaneous lesions in mice [mean volume for the noncloned strain, 75.45 +/- 4.43 mm3 (n = 70); mean of means for cloned populations, 77.28 +/- 3.14 mm3 (n = 230)]. The latter, Balt 42, isolated from a woman with an in situ carcinoma of the cervix uteri, produced large subcutaneous abscesses in mice [mean volume for the noncloned strain, 202.28 +/- 12.53 mm3 (n = 55); mean of means for cloned populations, 200.48 +/- 13.72 mm3 (n = 264)]. The apparent homogeneity of T. vaginalis strains with regard to virulence reinforces the dependability of the subcutaneous mouse assay.

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