Comparison of virtual monochromatic series, iodine overlay maps, and single energy CT equivalent images in head and neck cancer conspicuity

Abstract

ObjectiveTo compare lesion conspicuity amongst DECT monochromatic series (40, 45, 50keV), and single-energy CT (SECT) equivalent images in head and neck squamous cell carcinomas (HNSCC). MethodsTwo readers compared DECT images to 70keV SECT equivalent series in 39 patients with HNSCC on lesion margin, enhancement, and overall conspicuity. ResultsThe 45keV and 50keV images were significantly better (p-values ≤0.001) than the SECT equivalent in lesion enhancement, margins, and overall conspicuity for both readers. Readers mostly preferred the 50keV monochromatic series. ConclusionDECT can provide better lesion visualization than SECT in HNSCC.