Comparison of value between transperineal template guided biopsy and transrectal biopsy

Abstract

Objective To compare the effectivity, accuracy and safety of transperineal template guided biopsy and transrectal biopsy for prostate cancer. Methods A total of 220 patients clinically suspected as prostate cancer were divided into transperineal template guided gruop(n=113) and transrectal gruop(n=107). Positive diagnostic rate for prostate cancer was compared. The patients were distributed into different PSA level subgroups including 0-4 ng/mL, 4-10 ng/mL, 10-20 ng/mL and more than 20 ng/mL. And complications including fever and infection, gross hematuria, urinary retention, rectal bleeding, and pain assessment postoperative were compared between the two groups. Results In the PSA 4-10 ng/mL subgroup, the positive rate of prostate cancer in the transperineal template guided group was significantly higher than that in the transrectal group(P 0.05). The incidence of fever and infection, gross hematuriarectal, and rectal bleeding in the transrectal group was significantly higher than that in the transperineal template guided group(P 0.05). In addition, the painscore at 24 h postoperative in the transperineal template guided group was significantly lower than that in the transrectal group(P<0.05). Conclusions The transperineal template guided prostate biopsy is an important method for the early diagnosis of prostate cancer, which is effective, accurate and safe. When PSA is in the gray area of 4-10 ng/mL, the positive rate of prostate cancer by transperineal template guided biopsy is higher. Due to complications and pain are less, which makes most patients more acceptable, it should be better promoted. Key words: Prostatic Neoplasms; Biopsy, Needle; Perineum; Rectum