Comparison of Urodynamic Bladder Dysfunction in Male Patients with Pelvic Organ Malignancies

Abstract

Objective: Bladder dysfunction is a common complication after pelvic cancer treatments (radical pelvic surgery or chemoradiotherapy) that may affect patient satisfaction and quality of life. The aim of this study is to compare urodynamic bladder dysfunction among male patients with different pelvic organ malignancies (POMs). Materials and Methods: Data were collected from male patients with POM undergoing urodynamic studies (UDSs). Patients were stratified into three groups based on the origin of cancer (prostate, bladder, and colorectum). Selected data, including age, clinical tumor staging, lower urinary tract symptoms or acute urinary retention, and the parametric values of UDSs, were compared among the groups. SPSS 17.0.1 for Windows and Microsoft Office Excel 2007 were used for all statistical analysis. Results: A total of 640 patients with POM from the prostate (40.9%), bladder (33.5%), and colorectum (25.6%) were investigated. Patient age ranged from 39 to 89 years (mean 72.93 ± 9.08 years). In uroflowmetry (525 patients), the maximal urine flow rate was significantly lower in the prostate group (11.49 ± 5.53 ml/s). Cystometrograms (115 patients) showed that the first desire was more sensitive in the bladder group (85.52 ± 49.78 ml). Cystometric capacity was decreased in the prostate group (161.50 ± 94.29 ml); the maximum voiding pressure and compliance were significantly lower in the colorectum group (64.58 ± 50.09 cmH2O). Conclusion: Patients with POM may suffer from urination dysfunction. Impaired bladder function is more predominant in the colorectum oncology compared with urological pelvic organ (prostate or bladder) malignancies. Physicians are encouraged to be aware of these urinary complications after POM treatment.