Abstract
Objective To compare the clinical efficacy and safety of unipedicular versus bipedicular percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures.Methods Enrolled for this study were 101 patients with osteoporotic vertebral compression fracture who had been treated by PVP in our department from January 2009 to January 2012 and followed up for at least one year.They were divided into 2 groups according to the approaches they used.In the unilateral group,there were 45 patients,11 males and 34 women,with a mean age of 69.4 ± 10.4 years; in the bilateral group,there were 56 patients,6 males and 50 women,with a mean age of 69.7 ± 9.7 years.The 2 groups were compared in terms of operation time,bone cement volume injected,cement leakage,vertebral height restoration,kyphosis correction and visual analogue scale (VAS) score.Results The unipedicular group incurred significantly shorter operation time (36.4±6.0 min) and significantly less bone cement volume injected (3.72 ± 1.09 mL) than the bipedicular group (52.9 ± 6.8 min and 4.29 ± 1.12 mL respectively) (P ＜ 0.05).There were no significant differences between the 2 groups in anterior vertebral height restoration,middle vertebral height restoration or kyphosis correction (P ＞ 0.05).The VAS scores at 24 hours,3 and 12 months postoperation were significantly lower than preoperation in both groups (P ＜ 0.05),but there were no such significant differences between the 2 groups (P ＞ 0.05).The cement leakage rate for the unipedicular group [28.9％ (13/45)]was insignificantly lower than that for the bipedicular group [46.4％ (26/56)] (P ＞ 0.05).Conclusions Both unipedicular and bipedicular PVP can obtain satisfactory analgesia for the treatment of osteoporotic vertebral compression fractures but the former may have advantages of less invasion and shorter operation time. Key words: Spinal fractures; Osteoporosis; Fractures, compression; Vertebroplasty
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