Comparison of two Registries of Acute Coronary Syndrome in Argentina: STRATEG-SIA and SCAR (1999-2011)

Abstract

Background: The influence of clinical evidence on strategies implemented in the treatment of non-ST-segment elevation acute coronarysyndromes (NSTEACS) is not known in our setting.Objectives: The aim of this study was to evaluate the differences in clinical characteristics, strategies adopted, therapeutic managementand in-hospital events of NSTEACS in participatingcenters from two registries in Argentina.Methods: Patients included in participating centers of the STRATEG-SIA registry (1999) and SCAR registry (Sindromes CoronariosAgudos en Argentina - 2011) were compared.Results: We analyzed 238 patients of the STRATEG-SIA registry and 452 of the SCAR registry in 36 centers. Most patients weremen and <65 years (SCAR 57%, STRATEG-SIA 54%; p=ns). The SCAR group presented higher prevalence of hypertension (75%vs. 60%; p=0.001), dyslipidemia (63% vs. 51%; p=0.003), chronic heart failure (10.5% vs. 4.6%; p=0.02) and history of myocardialrevascularization (30% vs. 17%; p=0.001). In the SCAR registry, the proportion of moderate and high-risk patients (TIMI risk score3-4: 48% vs. 37%; 5-7: 18% vs. 8%; p=0.0001) was higher and coronary angiography was more frequent (71% vs. 50%; p=0.0001),with a twofold increase in the proportion of percutaneous coronary interventions and 50% reduction in the number of myocardialrevascularization surgeries. There were no significant differences in the rate of mortality and myocardial infarction during hospitalization(7.2% vs. 5.9%; p=ns).Conclusions: Patients of the SCAR (2011) registry represent a group at higher risk. The differences in the rates of in-hospital eventswere not statistically significant.