Abstract
Values for the time constant of reactivation of the sodium conductance following depolarization sufficient to completely inactivate GNa have been compared over a 15 mV range of membrane potential with the time constants of inactivation during a depolarization prepulse. Over this range the reactivation time constants were consistently 30-50% larger than the inactivation time constants determined simultaneously at the same potential in the same axon. The data suggests that inactivation and reactivation do not occur by identical mechanisms, and therefore implies that there are at least three kinds of experimental procedures necessary to fully characterize the sodium inactivation process in any particular system.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
