Comparison of two kinds of noninvasive ventilation mode in premature infants with respiratory failure

Abstract

Objective To investigate the difference of two models of respiratory failure in preterm infants with nasal continuous positive airway pressure(nCPAP) and nasal biphasic positive airway pressure(nBiPAP). Methods Comparative analysis of 81 cases of premature infants with respiratory failure requiring respiratory support was needed.They were applied nCPAP and nBiPAP ventilation mode treatment.The use of breathing machine and total oxygen inhalation time, the number of treatment failures, the PEEP parameters of the ventilator, the total number of recent complications and secondary infections were compared. Results In the nBiPAP treatment group, the average time of noninvasive ventilation was(96.34 ± 31.5)h, the total time of oxygen inhalation was(10.11 ± 9.39)d, 3 cases of treatment failure, the incidence of severe complications was 5.56%(2/36), PEEP(4.08±0.73)cmH2O(1 cmH2O=0.098 kPa). In the nCPAP group, the average time of noninvasive ventilation was(114.14±41.69)h, the total time of oxygen inhalation was(17.53±15.96)d, 15 cases were failed, the incidence of severe complications was 15.56%(7/45), PEEP(5.11±1.01)cmH2O.There were significant differences between the two groups(P 0.05). Conclusion nBiPAP as one of the first choice treatment for premature infants with respiratory failure significantly better than nCPAP, as soon as the proper use can avoid invasive ventilation. Key words: Positive airway pressure; Mechanical ventilation; Preterm infants; Newborn; Respiratory failure