Abstract
Aim: To evaluate the effect of postoperative irrigation with chlorhexidine saline irrigation and metronidazole saline irrigation on non-inflammatory complications after the extraction of lower third molar under local anesthesia.
 Materials and Methods: In this study a total of 120 patients with age range 18-80 years who had impacted tooth which required surgical removal were included. The patients were separated into two groups using Block Randomization to avoid sampling bias. Group A and Group B had 60 patients each. Group A patients were irrigated with 1% Chlorhexidine Saline and Group B patients were irrigated with 1% Metronidazole Saline during the surgical removal of their mandibular third molars. The patients were measured for the pain, swelling and checked for dry socket after 7 days of procedure.
 Results: The mean age of the patient was 28.08 + SEM years. Out of three parameters (Pain, Swelling, Dry Socket) assessed, only alveolar osteitis showed a statistical significant difference between 1% Metronidazole and 1% Chlorhexidine with p value 0.041(>0.05). Trismus and pain did not differ significantly (p>0.05) in the two groups with p-values of 0.431 for trismus and 0.750 for pain.
 Conclusion: Metronidazole had better efficacy in alveolar osteitis, while in the other parameters viz, pain and mouth opening there was no difference in the two treatments.
Highlights
2.2 Study DesignRemoval of impacted wisdom tooth is the most common dental surgical procedure performed in dental surgery
Trismus, swelling, or anatomical variation after the removal of a third molar can make the maintenance of oral hygiene difficult, and the accumulation of food debris around the surgical site increases the risk of infection and dry socket when lower wisdom teeth have been removed because of the effects of gravity [1]
Most commonly mandibular molars are involved in impaction [15], and this t study was based on the impacted mandibular molars
Summary
Removal of impacted wisdom tooth is the most common dental surgical procedure performed in dental surgery. Irrigation solutions play an important role in the surgical removal of impacted teeth. Irrigating solution that is used during surgical removal of the wisdom tooth does prevent injury to the bone and irrigates the working field and improves the vision of the dentist. Adding antibiotics to the normal saline irrigation during surgical guttering of the bone when surgically removing the third molar may help in the removal of iatrogenic microbes. In this study we aimed to compare the efficacy of 1% metronidazole saline irrigation and 1% chlorhexidine saline irrigation after surgical removal of the mandibular third molar
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