Abstract
Widespread escalation of type 2 diabetes is a concern throughout the world. Developing countries are leading with patients suffering from diabetes-related complications. Plant-based therapeutic, antidiabetic herbal preparations (ADHPs) are being sought for long and the consumption is increasing in in Bangladesh. Plant-based antidiabetic preparations do not go through the screening procedure in terms of safety. Toxic metals in ADHPs have been investigated by two different methods: atomic absorption spectroscopy (AAS) and X-ray fluorescence (XRF). Then, metal concentrations obtained by AAS and XRF were compared. A total of eleven ADHPs were subjected to nondestructive XRF analysis and destructive AAS analysis. Results from the two methods were analyzed statistically by Pearson correlation coefficient (PCC), rxy. Pearson correlation coefficients were found to be −0.05, 0.94, and 1.00 for Mn, Cu, and Zn, respectively. Zn and Cu had significant strong positive correlation (rxy = 1.00 and 0.94, respectively); however, very weak negative correlation was observed in Mn (rxy = −0.05). The concentrations were regressed to observe the presence of linearity. Linear correlation was found for Zn and Cu which indicates a good agreement between AAS and XRF. However, very weak linear correlation in Mn indicates necessitating requirements for further investigation on getting scientific evidence of toxic metal assessment of the antidiabetic herbal preparations for searching and establishing instrumental agreement.
Highlights
Approach towards the use of herbal preparations has occupied two different ways
All instances of Cu concentrations determined by X-ray fluorescence (XRF) and atomic absorption spectroscopy (AAS) in the supplied antidiabetic herbal preparations (ADHPs) (Table 3) exceeded recommended permissible concentrations set by the WHO/FAO
No instances for Mn determined by AAS and XRF passed safe limits set by the FAO/WHO (Table 3)
Summary
Approach towards the use of herbal preparations has occupied two different ways. One way leads to traditionalism which depends on empirical appreciation of medicinal herbs. A vast number of people are relying on herbal preparations for traditional belief and for the eagerness of a fraction of them to know the science and clinical practice behind these types of preparations. This curiosity of people has opened door which depends on traditionalism and in that new approach, blending between science and traditionalism has become possible. This curiosity of people has opened door which depends on traditionalism and in that new approach, blending between science and traditionalism has become possible. is way is known as phytotherapy [3]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
