COMPARISON OF THYROID HORMONES LEVEL IN NORMAL AND PREECLAMPTIC PREGNANCY

Abstract

To find a relationship between preeclampsia and thyroid dysfunction by comparing serum levels of Free T3 (fT3), Free T4 (fT4) and TSH in preeclampsia and normal pregnancy. The study was conducted within 6 months from May 2018 to November 2018, on the patients who attended OB/GYN department of Sohag Faculty of Medicine, Institutional review board approval was obtained April 2017. 30 of them were diagnosed as preeclamptic [blood pressure after 20 weeks of gestation is raised to 140/90 mm of Hg or more or have mean Blood Pressure. (diastolic+1/3rd pulse pressure) of more than 110 mm of Hg] with presence of proteinuria and/or edema. 30 age-matched normotensive pregnant women. Blood pressure was measured (auscultatory and palpatory) in semi sitting position using sphygmomanometer. Both groups had no history of thyroid dysfunction. According to the International Society for the Study of Hypertension Pre-eclampsia is defined as blood pressure ≥140/90 mmHg on two separate occasions 6 hours apart or a single recording of a diastolic blood pressure of 110 mmHg, in association with proteinuria ≥1+ on dipstick urine testing (Dawn C. Scantlebury, et al., 2013)