Abstract
Objective To compare three general anesthesia methods for retrieve of endobronchial foreign body in children.Methods Three hundred children undergoing endobronchial foreign body retrieve were randomly assigned into three groups:group A (ketamine +pethidine +midazolam +dexmedetomidine),group B (ketamine +fentanyl +midazolam +cis-atracurium),group C (sevoflurane +propofol +remifentanil +succinylcholine).The time required for endobronchoscope insertion,difficulty grade of endobronchoscope placement,and times of the procedure interruption caused by body movement or desaturation were recorded.The artery oxygen saturation (SpO2) and heart rate (HR) were closely monitored during the anesthesia.The HR and SpO2 at entering the OR (T0),endobronchoscope placement (T1),and the end of the procedure (T2),and the time required for consciousness recovery (T3) were observed.The arterial blood-gas analysis was performed at the end of the procedure.The times required for procedure andrecovery were also recorded.Results In group A,HR was (106±9) beats/min,(99±9) beats/min and (97±10) beats/min at observed points of T1,T2 and T3,respectively,time required for recovery was (118±10) min.The breath holding was observed in group A but without carbon dioxide accumulation.In group B,time required for recovery was (58±7) min,Compared to group A and group C,group B had a quicker recovery time and faster HR(P＜0.01).No breath holding was noted in group B but with obvious carbon dioxide accumulation.Group C had the shortest recovery time (21±5) min,a relative stable HR and no breath holding during anesthesia,but with some extent of carbon dioxide accumulation compared to group A and group C (P＜0.01).The rate of hypoxemia was not statistically different among three groups.Conclusions The three general anesthesia methods described above have their advantages and disadvantages.They should be selected based on the physical conditions of the patients and proficiency of the anesthesiologist. Key words: Foreign body; Anesthesia
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