Comparison of the two diagnostic criteria of metabolic syndrome among hypertensive population

Abstract

Objective To compare the application of National Cholesterol Education Program′s Adult Treatment Panel Ⅲ (NCEP/ATP Ⅲ) and Chinese Diabetes Society (CDS) diagnostic criteria of MS in hypertensive population. Methods Anthropometry and blood pressure were measured and bio-specimens were collected in 7 485 hypertensive patients. The detection rate of MS using NCEP/ATP Ⅲ criteria and CDS criteria in patients with hypertension were compared and the accordance of the two diagnostic criteria were studied. Characteristics of distribution of detection rate in different sex, age and metabolic abnormity were analyzed. Results The overall detection rate of MS was 39.4% (n=2 949) and 42.5% (n=3 181) according to NCEP/ATP Ⅲ and CDS diagnostic criteria, respectively. The detection rate of CDS criteria was higher (χ2=454.19, P<0.001). The detection rate of MS was higher in males than in females using CDS criteria but this sex difference was reversed when using the NCEP/ATP Ⅲ criteria (χ2=365.58, P<0.001). The changing trend with aging were no different between the two criteria, the prevalence increased with age (χ2=425.51, P<0.05). Conclusion Compared with the NCEP/ATP Ⅲ criteria, the detection rate of MS by the CDS criteria is higher in hypertensive patients. Key words: Metabolic syndrome; Hypertension; NECP/ATP Ⅲ; CDS