Comparison of the safety and effectiveness of holmium laser enucleation of the prostate and transurethral resection of the prostate

Abstract

Objective To compare the safety and effect of the holmium laser enucleation of the prostate(HoLEP) and transurethral resection of the prostate(TURP) for benign prostatic hyperplasia(BPH). Methods Three hundred and forty-nine cases with benign prostatic hyperplasia were divided into HoLEP group(172 cases) and TURP group(177 cases). All patients were assessed preoperatively, then we recorded hemorrhage volume, operation time, catheter indwelling time and complication rate. Follow-up 3 months, postvoid residual(PVR), maximal urinary flow rate(Qmax), international prostate symptom score(IPSS), quality of life score(QOL) were analyzed. Results Hemorrhage volume, operation time, catheter indwelling time in HoLEP group were significant less than TURP group(P<0.05), complication rate of HoLEP group was lower than that of TURP group(P<0.05). After 3 months follow-up, IPSS, Qmax, PVR, QOL were obviously improved in both groups compared with preoperation(P<0.05). Conclusions HoLEP is safer than TURP on the base of same effectiveness, it is an promising surgical method for BPH patients. Key words: Prostatic hyperplasia; Holmium; Lasers; Transurethral resection of prostate