Comparison of the Predictability, Uniformity and Stability of a Laser in Situ Keratomileusis Corneal Flap Created with a VisuMax Femtosecond Laser or a Moria Microkeratome

Abstract

This prospective study compared the predictability, uniformity and stability of laser in situ keratomileusis corneal flap thickness created by a femtosecond laser or a classic microkeratome. Twenty-five femtosecond laser (VisuMax, Carl Zeiss Meditec) flaps and 38 microkeratome (Moria M3) flaps were measured using anterior segment optical coherence tomography at 1 week, 1 month and 6 months postoperatively. Flap thickness at seven points on each of the four meridians was calculated. At 6 months, VisuMax flaps showed better prediction than Moria flaps for central flap thickness. The standard deviation within individual flaps was smaller for VisuMax flaps and their index of symmetry was better. The mean thicknesses among the four eccentricities in the VisuMax flaps were the same, while Moria flaps were thicker at the 3-mm radius compared with the centre. The VisuMax femtosecond laser created corneal flaps with better predictability and uniformity, and similar reproducibility and stability, compared with the microkeratome.