Abstract
Introduction This study sought to compare patients with ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction in terms of the monocyte-to-HDL cholesterol ratio. Materials and Methods A total of 79 patients with non-ST-segment elevation myocardial infarction and 30 patients with 30 ST-segment elevation myocardial infarction were included in the study. Demographics, comorbidities, smoking status, medical history, and initial laboratory findings were retrospectively noted from the hospital computer-based patient data system. Results Significant differences were detected between the ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction groups in relation to the neutrophil count [7.27 (6.05-9.05) versus 5.41 (4.26-7.21), p<0.001] and mean platelet volume [9.4 (8.8-10) versus 8.6 (7.3-9.5), p=0.002]. There was no statistically significant difference between the two groups in the term of the monocyte-to-HDL cholesterol ratio [0.016 (0.012-0.021) versus 0.016 (0.011-0.024), p=0.757, Bonferroni-corrected p value: 0.0033)]. Conclusion Based on the results of our study, the monocyte-to-HDL cholesterol ratio did not significantly differ between the patients with ST-segment elevation myocardial infarction and those with non-ST-segment elevation myocardial infarction.
Highlights
This study sought to compare patients with ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction in terms of the monocyte-to-high-density lipoprotein (HDL) cholesterol ratio
Researchers have reported that the combination of monocyte count, which represents the pro-inflammatory effect of the monocytes, and high-density lipoprotein (HDL) cholesterol, which represents antioxidant and anti-inflammatory effects, can be used as a biomarker in Journal of Clinical Medicine of Kazakhstan: 2021 Volume 18, Issue 6
Patients with unstable angina pectoris (USAP), cases in which acute coronary syndrome (ACS) could not be confirmed with percutaneous coronary intervention, and patients with missing data were excluded from the sample
Summary
This study sought to compare patients with ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction in terms of the monocyte-to-HDL cholesterol ratio. Results: Significant differences were detected between the ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction groups in relation to the neutrophil count [7.27 (6.05-9.05) versus 5.41 (4.26-7.21), p
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