Comparison of the main parameters of 24-hour blood pressure monitoring in patients with hypertension and atherosclerotic lesions of the arteries of the lower extremities

Abstract

Objective: To study the features of the parameters of 24-hour blood pressure monitoring (24h-BPM) in patients with hypertension and atherosclerosis of the arteries of the lower extremities (AALE).Materials and Methods: A total of 120 patients with hypertension were divided into 3 groups: Group I consisted of 46 patients with hypertension and clinically manifested AALE; Group II included 39 patients with hypertension and asymptomatic AALE; Group III included 35 patients with hypertension without AALE. Laboratory and instrumental studies were performed, including 24h-BPM and ultrasound triplex scanning (USTS) of the arteries of the lower extremities. Statistical analysis was performed using Microsoft Office Excel 16 (2015, Microsoft, USA), Statistica 10.0 (StatSoft, USA), IBM SPSS Statistica 26.0 (IBM, USA).Results: Higher values of systolic blood pressure (SBP) were revealed in Group I patients compared with Group III (P <0.05). Increased variability of daily average and daytime SBP were found in Group I patients (16 [13; 17] and 15.5 [12; 18] mm Hg), which significantly differed from those in Group III (P = 0.005). The patients of Group II showed higher values of diastolic blood pressure (DBP) compared with Group I (P <0.017). Higher values of pulse blood pressure (PBP) were found in Group I compared with Groups II and III (P = 0.001). In Group I, the normal type of 24-hour index of SBP was 2 times less common (P <0.017).Conclusions: The clinical manifestation of AALE is associated with higher SBP and PBP values, SBP variability and lower DBP values, which indicates a higher risk of cardiovascular complications.