Abstract

Objective: Postoperative superficial surgical site infection (SSI) is one of the major complications in hepatobiliary-pancreatic (HBP) surgery. The purpose of this study was to compare the efficacy of subcuticular sutures versus staples for skin closure in the prevention of superficial SSI in HBP surgery. Method: Data for patients who underwent HBP surgery at our hospital from 2006 to 2015 were reviewed retrospectively. The incidence of superficial SSI was evaluated in two groups: subcuticular sutures and staples. Propensity score matching (PSM) analysis was used to control for any bias from confounding factors. Results: A total of 691 patients were included. The first group consisting of 346 patients with skin staple was compared with a second group of 345 patients with subcuticular suture. After PSM analysis, significant difference in the incidence of superficial SSI was found between the stapler (11.4%) and the subcuticular sutures (2.6%) (P < 0.001). The same comparison was performed in subgroup analyses supporting this finding in patients after hepatectomy without biliary reconstruction, pancreatoduodenectomy, open laparotomy, and patients with body mass index under 25. Conclusion: After controlling for potential bias, subcuticular suture use after HBP surgery was more efficacious in reducing the incidence of superficial SSI than the staples.

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