Comparison of the Efficacy of Different Surgical Approaches for Complicated Impacted Proximal Ureteral Calculi Based on a New Scoring Standard: A Matched-Pair Analysis.

Abstract

Objective: To compare the clinical efficacy of ureteroscopic lithotripsy (URSL) and percutaneous nephrolithotomy (PCNL) in the treatment of complicated impacted proximal ureteral calculi using a new scoring standard. Methods: The data of 45 patients with complicated impacted proximal ureteral calculi (score ≥3 points) who underwent URSL were collected in this retrospective study between January 2015 and April 2021. The definition and scoring standards for preoperative high-risk factors associated with stones included whether the diameter of the stone was >2 cm, stone density was >1000 HU, there was a history of lithotripsy, the degree of hydronephrosis was greater than moderate, and there was an infection. Scores for stones were then assigned (yes = 1, no = 0), and the complicated stone case was defined as a total stone score ≥3 points. During the same period, PCNL was used in 171 patients with complicated impacted proximal ureteral calculi. Forty-five patients were selected as the control group and matched at a 1:1 ratio to index URSL cases regarding age, sex, and body mass index. Perioperative data were compared between the two groups. Results: All 90 operations were completed effectively. Compared to the URSL group, the surgical duration of the PCNL group was significantly shorter (53.69 ± 25.07 vs 73.46 ± 27.12 minutes, p < 0.05), stone-free rate (SFR) was significantly higher (93.3% vs 68.9%, p < 0.05), and total treatment cost was lower (US $1678.61 ± 714.86 vs US $3901.45 ± 1069.46, p < 0.05). Conversely, the URSL group had a shorter hospital stay (3.68 ± 2.70 vs 6.39 ± 3.34 days, p < 0.05). There was a significant difference in complication rate between the two groups regarding Clavien grade I, II, or III complications (20.0% in URSL group vs 8.9% in PCNL group, p = 0.037). Conclusion: PCNL had a better SFR and higher surgical efficacy, whereas URSL had a shorter perioperative period, but a lower initial SFR. PCNL is often more advantageous for complicated impacted proximal ureteral calculi.