Comparison of the efficacy for venous indwelling needle on the different concentrations of calcium gluconate intravenous infusion in infants

Abstract

Objective To explore the optimum dilution concentration of calcium gluconate intravenous infusion in infants and the detaining time of venous indwelling needle .Methods One hundred and thirty-nine infants who needed calcium gluconate intravenous infusion were chosen and divided into the one time dilution group （n=43）, two times dilution group （n=48）, and five times dilution group （n=48）.The incidence of extravasation injury in puncture vascular , the degree of injury and the situation of healing were compared among three groups .Results The total incidence of extravasation injury in puncture vascular in the one time dilution group, two times dilution group , five times dilution group within 3 days were respectively 19.4%, 9.0%, 2.1%, and the differences were statistically significant （H=261.23, P〈0.01）.The further analysis showed that the incidence of extravasation injury in the one time dilution group was higher than that of two times dilution group （χ2 =6.88, P〈0.01）, and the incidence in the two times dilution group was higher than that of five times dilution group （χ2 =6.40, P〈0.05）, and the incidence in the one time dilution group was higher than that of five times dilution group （χ2 =20.48, P 〈0.01 ）.No difference was found in the incidence of extravasation injury in puncture on the first , second and third day of the detaining time of venous indwelling needle （H=3.47,P〉0.05）.Conclusions The incidence of extravasation injury is lowest in 5 times diluted concentration of 10%calcium gluconate intravenous infusion in infants through venous indwelling needle . Key words: Calcium gluconate; Drug concentration; Venous indwelling needle; Infant