Abstract
Interactions of FK 506 with renal cortical mitochondria have been investigated by measuring respiration, ATP net uptake and Ca 2+/P iinduced swelling. Both FK 506 and cyclosporin A (CsA) inhibit the succinate-supported state 3 and uncoupled respiration and are without effect on the glutamate/ malate-supported state 3 and uncoupled respiration. FK 506, like CsA, inhibits net uptake of ATP, but, in contrast to CsA, is without effect on Ca 2+/P i-induced swelling.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
