Abstract
To determine the effect of intranasal (IN) and intramuscular (IM administration of zolazepam-tiletamine (ZT) combination on intraocular pressure (IOP). Both eyes of 8 clinically normal cats were used. The animals received 10 mg/kg dose of ZT combination by IN and IM routes with a 7-day interval between treatments. IOP values were measured at baseline (T0) and at 10, 15, 20, 25, 30, and 45 min in both treatment groups. There were no statistically significant differences between baseline and post-treatment IOP measurements. The IOP did not change over time regardless of administration route. ZT combination did not have a significant effect on IOP in cats, when administered by IM or IN routes.
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