Abstract
Introduction: One of the concerns of painless deliveries is the safety of neonates. This clinical trial study aimed to compare the effects of epidural and spinal anesthesia on the mortality rate of neonates.
 Methods: This clinical trial was conducted in Hamadan Hospital in Iran. Ninety women, ages 18 to 45, were randomly assigned to receive epidural or subdural anesthesia. Using a checklist, the following were collected: demographic information, midwifery, hemodynamic status, mothers' pain intensity, and analyses of the baby's umbilical cord blood. The data were analyzed by SPSS version 16 for statistical analysis. Twenty-two of the patients with spinal anesthesia and epidural anesthesia were excluded from the study.
 Results: There was no significant difference between the two groups in terms of age, gestational age, parity, and severity of pain before or after anesthesia. The hemodynamic status of the mothers before and during the first postoperative period was in the normal range, except that in the spinal group, a decrease in systolic blood pressure was observed in normal range compared with the epidural anesthesia group. In blood gas analysis, the mean pH, partial pressure of carbon dioxide (PCO2), and bicarbonate (HCO3) did not show significant differences between the two groups (p > 0.05). The only complications were acidosis and epidural anesthesia.
 Conclusion: Based on the findings of the present study, both spinal and epidural opioids have no adverse effects on the health of neonates. However, both spinal and epidural opioid are preferred due to fewer changes in the hemodynamic changes in mothers and in umbilical cord blood gas.
Highlights
One of the concerns of painless deliveries is the safety of neonates
The hemodynamic status of the mothers before and during the first postoperative period was in the normal range, except that in the spinal group, a decrease in systolic blood pressure was observed in normal range compared with the epidural anesthesia group
Limitations included the number of patients to participate in this study of the magnitude of pain inten-. In this clinical trial study, 90 pregnant women were nominated for a normal vaginal delivery and without pain control patients were split into 2 respective groups: epidural (2) and spinal anesthesia (2)
Summary
Pregnancy is carried out in a variety of ways which include standard vaginal delivery and cesarean section. Natural childbirth is carried out in two ways- with painless and without pain control. One of the essential methods used to reduce the extent of labor pain in the developed world in recent decades is the use of such local epidural and spinal anesthesia 2. Inadequate control of labor pain is associated with adverse effects on both the mother and fetus. Comparison of the effects of epidural and spinal anesthesia on analgesia and blood gases in neonates born by natural vaginal delivery: A clinical trial study. One of the challenges of local anesthesia (e.g. spinal or epidural) is their effects on the fetus and its hemodynamic status. Epidural anesthesia causes pain reduction, which is associated with increased breathing rate; changes of hemoglobin in the mother can have a negative effect on neonatal hemoglobin 5. Given the lack of studies in the field, as well as lack of policy in the country to promote natural childbirth, this clinical trial study was aimed at comparing epidural and spinal anesthesia in newborn babies
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