Abstract
ObjectiveTo compare the mean change in peak expiratory flow values in children receiving inhaled beclomethasone dipropionate versus inhaled budesonide in the treatment of mild persistent asthma.MethodThe medical records of 60 patients from the outpatient department (OPD)/emergency room (ER), National Institute of Child Health, Karachi, who received beclomethasone dipropionate (BDP) 200 µg one puff and budesonide (BUD) 200 µg one puff twice a day for treatment of mild persistent asthma from March 10, 2020, to August 10, 2020, were explored.ResultsThe mean age of children was 10.56 ± 3.01 years in the BUD group and 10.05 ± 3.54 years in the BDP group. The mean change in peak expiratory flow % in the BUD group was 15.69 ± 3.59%, and in the BDP group, it was 13.59 ± 4.26% (P-value=0.04)ConclusionBDP and budesonide (BUD) were both found to be effective for the treatment of mild persistent asthma in children. However, we found that BUD had better efficacy compared to BDP.
Highlights
Asthma is a common illness of childhood in which chronic inflammation of the airways are a characteristic feature
This inflammatory disorder of chronic nature requires frequent monitoring and timely intervention for preventing irreversible and long-term pulmonary function impairment. It can significantly decrease the quality of life, especially in children through retardation of growth, exercise inability, insomnia, and frequent absenteeism from school [1]
Asthma attacks can become so serious that a person needs medical treatment, or they can result in death
Summary
The medical records of 60 patients from the outpatient department (OPD)/emergency room (ER), National Institute of Child Health, Karachi, who received beclomethasone dipropionate (BDP) 200 μg one puff and budesonide (BUD) 200 μg one puff twice a day for treatment of mild persistent asthma from March 10, 2020, to August 10, 2020, were explored
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