Abstract
Background Many dental procedures begin with local anesthesia. Subsequent increase in blood pressure in healthy individuals commonly occurs and may be affected by several factors such as mental and physical stress, painful stimuli, and action of catecholamines present in local anesthetic solutions. The aim of the present study is to compare the effects of 4% articaine with 1 : 100000 epinephrine and 2% lidocaine with 1 : 80000 epinephrine on blood pressure after maxillary infiltration technique. Materials and Methods In this randomized clinical trial, 102 patients were randomly assigned into two groups. One group received 4% articaine with 1 : 100000 epinephrine and the other group received 2% lidocaine with 1 : 80000 epinephrine for local maxillary infiltration. Systolic and diastolic blood pressure of both groups was determined twice: once before anesthetic injection and once 10 minutes after injection. The data were statistically analyzed using descriptive statistics, Shapiro–Wilks test, Levene test, chi-square test, independent t-test, and paired t-test. Results The mean systolic blood pressure after anesthetic injection in the articaine and lidocaine groups was 125.00 ± 5.67 and 123.16 ± 6.417 mmHg, respectively, showing no statistically significant difference (p=0.127). The mean diastolic blood pressure after injection was 85.02 ± 7.331 in the articaine group and 81.35 ± 12.815 mmHg in the lidocaine group. These values show no statistically significant difference (p=0.080). In both groups, the mean systolic and diastolic blood pressures have increased significantly (p < 0.001). Conclusion Articaine can be regarded as a suitable alternative for lidocaine for maxillary local infiltration, as no significant difference was observed between the effects of the two anesthetic solutions on blood pressure.
Highlights
Many dental procedures are preceded with local anesthesia
Increased blood pressure is common after injection of local anesthetic drugs [2]. e amount of this increase is modified by several factors such as psychological and physical stress, painful stimuli, and catecholamines present in dental anesthetic solutions [3, 4]
E routine injection technique for anesthesia of maxillary teeth is infiltration technique. e literature regarding comparison of maxillary infiltration of lidocaine and articaine anesthetic solution is scarce. erefore, the aim of the present study was to evaluate the effects of 4% articaine with 1 : 100000 epinephrine on blood pressure after maxillary infiltration technique
Summary
Many dental procedures are preceded with local anesthesia. Anesthetic drugs are among the most common drugs used in dentistry. E mean systolic blood pressure after anesthetic injection in the articaine and lidocaine groups was 125.00 ± 5.67 and 123.16 ± 6.417 mmHg, respectively, showing no statistically significant difference (p 0.127). Ese values show no statistically significant difference (p 0.080) In both groups, the mean systolic and diastolic blood pressures have increased significantly (p < 0.001). Articaine can be regarded as a suitable alternative for lidocaine for maxillary local infiltration, as no significant difference was observed between the effects of the two anesthetic solutions on blood pressure
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