Comparison of the effectiveness of savlon antiseptic with povidone-iodine for acinetobacter baumannii infected wounds in white rats (Rattus Norvegicus)

Abstract

Wound washing with antiseptic liquid is one step in the management of chronic wounds. In infected wounds, washing with antiseptic is expected to reduce bacterial colonies and help eradicate infection. One of the important pathogenic bacteria is Acinetobacter Baumannii. These opportunistic germs can form colonies, especially in patients receiving broad-spectrum antibiotic therapy, treatment in the ICU, and on skin affected by burns. Antiseptic commonly used to wash wound are Savlon and Povidone-iodine 10%. Both antiseptic are broad spectrum antisepctic, kill gram negative and gram positive bacteria. However Savlon could caused skin irritation. Therefore dilution is needed to prevent this effect. This study was intended to determine the difference and comparison of the effectiveness of Savlon and Povidone iodine antiseptic to bacterial growth on wound infected by Acinetobacter Baumannii. This study is an experimental study with a randomized controlled trial without blinding. The wound research procedure was made on the right and left sides of the rat's back with a size of 1x1 cm each. Wounds that have been contaminated with Acinetobacter Baumannii are left for 4 hours. After 4 hours the wound will be washed and irrigated. The wound that has been made is closed with a transparent dressing.