Comparison of the Effect of Triclosan Coated Polyglactin Sutures and Plain Polyglactin Sutures on Post-operative Healing in Patients Undergoing Surgical Removal of Mandibular Third Molar (MTM)

Abstract

Background: Surgical site infection (SSI) has been ruled out as having the highest prevalence among infections associated with avoidable health care. The application of coatings and other treatments to medical devices to avoid bacterial colonisation has gotten a lot of press recently. Bacterial growth should be prevented rather than treated because once bacteria have formed a habitat, they form a biofilm that prevents antibiotics from penetrating the infection site. As a result, it would be necessary to incorporate an antimicrobial agent into medical devices.
 Objectives: The study's main goal is to see how successful, Triclosan Coated polyglactin suture as a wound closure agent in terms of surgical site infection after surgery, bacterial colonization, trismus and pain over the plain conventional one.
 Methodology: Two groups (Group-I & Group-II) with 15 individuals as subjects are considered for the study model. Systemically healthy individual with presence of mandibular third molar (MTM) with similar difficulty index, depth of, and relationship with ramus will be included in the study sample. Wound closure would be achieved by using antimicrobial triclosan-impregnated 3–0 polyglactin sutures for closing the surgical site using simple interrupted sutures (Group-I) and plain 3–0 polyglactin sutures for closing the surgical using simple interrupted sutures (Group-II), respectively. Post-operatively measurement of surgical site infection, bacterial colonization, trismus and pain will be done.
 Expected Results: Polyglactin sutures coated with triclosan for closure of wound after MTM surgery, will be successful in minimising post-operative surgical site infection, bacterial colonization, trismus and pain.
 Conclusion: Use of polyglactin sutures coated with triclosan, aids in the prevention of one of the most prevalent postoperative conditions, surgical site infection(SSI) and to reduces bacterial colonization, trismus and pain. The surgeon's and the patient's need for a positive cosmetic outcome postoperatively is hampered if a postoperative surgical site infection develops, which one can be overcome by their usage.