Abstract
This study involved the effect of the aqueous extracts of two plants, Origanum vulgare L.(1), Trigonella Foenum Graecum L. (Fenugreek) seeds(2) on the growth of cancer cell lines. Rhabdomyo sarcomas (RD) of human cell line and female intestine cells of Albino mice (L20B) in vitro System. These extracts were compared with the known anticancer drug Cis-platinum(Cis-Pt) as a positive control. The phytochemical tests were used for screening the active compounds in plants. The inhibition activity assay was used as a parameter of the cytotoxic effect of these extracts. Cancer cell lines were treated with four concentrations of Cis-platin, 31.25, 62.5, 125 and 250 ?g/ml for 72 hour exposure time. The same concentrations were used for the other extracts. This study found that the two aqueous extracts (1,2) have a cytotoxic effects on cancer cells as could be seen from their effects on inhibition percentage and the significant differences (p
Highlights
According to the world health organization(WHO), cancer is a leading cause of death world wide
The cytotoxic effects were tested for the three solutions on growth cancer cell lines L20B and Rhabdomyo sarcomas (RD)
The cell lines L20B and RD were treated with two aqueous extract (Origanum vulgare, fenugreek) and cis- platin using four concentrations (31,25, 62,5, 125, 250)μg ∕ lml .Immediatly adding 25 ml of trypsinversene solutions into culture bottle and 20 ml of culture medium which contains 10% of serum to provide the suspended cells, mixed very well and 0.2 ml was added to each microtiter
Summary
According to the world health organization(WHO), cancer is a leading cause of death world wide. The aim of this study is to compare between the cytotoxic effects of the aqueous extracts of two plants with that of the anticancer drug Cis-platin on growth cell lines (RD and L20B).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
