Abstract
Markers of acute inflammation are gaining broader acceptance in feline veterinary practice but the criteria of their diagnostic accuracy have mostly not been determined. The goal of this study was to compare the diagnostic accuracy of a variety of markers of inflammation that can be rapidly measured in everyday veterinary practice settings. White blood cell, as well as neutrophil and band cell count, degree of toxic neutrophilia, total proteins, albumin, albumin-to-globulin ratio, fibrinogen, and serum amyloid A protein were measured in 35 cats with acute inflammatory diseases and 16 control cats. The sensitivity, specificity, and receiver operating curves of these markers were then compared. The markers with the highest sensitivities and specificities, as well as areas-under-the-curve of the receiver operating curves > 0.9, were fibrinogen, serum amyloid A, degree of toxic neutrophilia, and albumin-to-globulin ratio. The correlations between the different markers were, with the exception of fibrinogen and SAA, low. SAA, fibrinogen, albumin-to-globulin ratio are a panel of sensitive inflammatory biochemistry biomarkers easily available for non specialist veterinarians improving the rapidity of feline patient assessment.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.