Abstract
1. Purified preparations of luteinizing hormone from bovine, ovine and human pituitary tissue have been compared with respect to carbohydrate and amino acid composition. 2. Sialic acid content varied from 0.3% for bovine and ovine LH to 2.0% for human LH; hexoses (galactose and mannose) were from 11 to 12%; and hexosamines (galactosamine and glucosamine) from 3 to 6 %. 3. All the preparations contained high concentrations of proline. Serine, threonine and glutamic acid were the next most abundant amino acids. 4. A similar pattern of amino acid composition for all the preparations was apparent, but ovine and bovine LH contained larger amounts of lysine and alanine, and lesser amounts of aspartic acid and valine, than did human LH. (Endocrinology81: 45, 1967)
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