Abstract
Up to 30% of the general population develops IgE against cross-reactive carbohydrate determinants (CCDs) found in insect venoms and plants and as a result are at risk of receiving false positive test results from specific IgE (sIgE) immunoassays. ImmunoCAP utilizes a cellulose-based matrix that is known to contain CCD N-glycans that bind to anti-CCD IgE antibodies. This abstract reports on the analysis and resolution of discordant results between NOVEOS and ImmunoCAP in two recent United Kingdom based National External Quality Assessment Service (UK NEQAS) samples.
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